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Bodybuilding SARMS Raw Powder Coluracetam MKC-231 BCI-540 135463-81-9 weight
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Hongkong Pengfei Pharmaceutical Technology Co.,Ltd2020-07-10 09:46:19
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Product Details
| skype: | nancynancy2614 | E-mail: | [email protected] | whatsapp: | +86 18872220734 |
| Product name: | Coluracetam | Other name: | MKC-231 BCI-540 |
Product Description
Bodybuilding SARMS Raw Powder Coluracetam MKC-231 BCI-540 135463-81-9
Basic information
Coluracetam 135463-81-9
Product Name: Coluracetam MKC-231
Chemical Name: N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-
1-yl)acetamide
No.: 135463-81-9
Formula: C19H23N3O3
Purity:99%
Molecular Weight:341.40
Appearance:white crystal powder
Boiling Point:634.1C at 760 mmHg C
Usage:
MKC-231, a putative cholinergic activity, is reported to improve learning and memory impaired in AF64A-treated animals. MKC-231 enhances high-affinity choline uptake (HACU) known as the rate-limiting step of acetylcholine (ACh) synthesis. We investigated the mode of action (MOA) of HACU enhancement by MKC-231. Intracerebroventricular (i.c.v.) injections of AF64A (3 nmol/brain) resulted in significant HACU reduction in hippocampal synaptosomes. Treatment with MKC-231 increased Vmax of HACU and Bmax of [3H]-HC-3 binding 1.6 and 1.7-fold, respectively. In studies of [3H]-MKC-231 binding and Biacore analysis, MKC-231 showed noticeable affinity for cloned high-affinity choline transporters (CHT1). The present study suggests that MKC-231 directly affects trafficking of CHT1 and increases the numbers of transporter, working for HACU, at the synaptic membrane.
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We are one of the leading manufacturers and exporters in China. We specialized in fine chemical, flavor, food additive, pharmaceutical and intermediates. If you have any questions of our products that you are interested in, please contact as without hesitate.
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YK11 431579-34-9
MK-1755 955365-80-7
MK-5172 1350514-68-9
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Bodybuilding SARMS Raw Powder Coluracetam MKC-231 BCI-540 135463-81-9 weight Images |
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