Pharma Raw Material SARM Powder Aicar Fat Burning Hormone Powder CAS 2627-69-2

 

Pharma Raw Material SARM Powder Aicar Fat Burning Hormone Powder CAS 2627-69-2

 

 

 

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AICAR Description:

AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in, but there are some amazing side effects.

 

Interestingly, AICAR has been shown to protect against ischemic injury. This type of injury is directly related to the restriction of blood to tissues, which can cause insufficient amounts of oxygen and glucose needed to keep the tissue alive. This can lead to thrombosis, embolisms, and vasoconstriction. AICAR can be used as a stabilizing peptide for ischemic episodes, and it can allow for proper blood flow to the myocardium (heart). This function is very interesting, as AICAR could be fundamentally used to treat the heart muscle in the aftermath of a heart attack. This might reduce the possibility for ischemic injuries. Abnormal growths of heart tissues and heart valve function have also been altered in animal studies that used the peptide AICAR, which is a downside.

 

Aicar Spec.

Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 98%
Apperance: White or off-white powder.
Grade:Pharmaceutical Grade
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases.acts by entering nucleoside pools, significantly increasing levels of
adenosine during periods of ATP breakdown

 

Functions:

AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

Dosage and Usage

Here is where AICAR becomes a pipe dream for anyone who is not a top level endurance athlete or bodybuilder. The dosages recommended to achieve the benefits from this peptide are insanely high. AICAR must be dosed at around 500mgs per kilogram (kg) of body weight. A gram of real pure AICAR can cost $100 USD or more, so single dosages for humans could be well in to the several hundreds of dollars! Some say that this can be circumvented by stacking it with Cardarine (GW), but you still need to spend a lot of money for perhaps little to no result if you are not dosing high enough dosages.
Yes, the peptide AICAR has amazing properties, some which even show the slowing of growth in cancer cells, but for the average athlete this has no basis in a day to day regiment. On the other hand, Cardarine (GW) has been shown to provide users with more than enough results as an Activated Receptor d agonists (PPARd) and its cost-effective for everyone.

 

Side Effects

The most concerning side effects from AICAR are the direct effects it has on your heart. It can cause enlarged growth in cardiac tissue, and it can effect blood flow. In turn, this could affect the flow of blood to a persons brain. In addition, it has been noted that defects of heart valves may also be caused by the peptide AICAR. The heart is the most important muscle in the entire body, and the last thing anyone wants to do is treat it badly. Anecdotally, some logs indicated extreme loose bowls, dry mouth, and lack of hunger.

 

Possible enlarged growth of heart
Possible defects to the heart valve
Problems with blood flow
Problems with blood and nutrient transfer to the brain
Problems with bowls

 

Conclusion

For the cost and the potential side effects, the peptide AICAR has no real use in the sports or bodybuilding world. It is touted as exercise in a bottle, but most athletes don want to sit around and do nothing, they actually enjoy being active and staying fit. This is why Cardarine is by far the more superior PPARd, as it is activated by exercise and has many of the same benefits that AICAR does without the extremely nasty side effects. Unless you are a professional endurance athlete with extra money to spend and need the very small edge over competition, there is very little reason to use AICAR

 

SARMs List

MK-2866 (Ostarine)
RAD-140 (Testolone)
MK-677 (Ibutamoren; Nutrobal)
LGD-4033 (Ligandrol; Anabolicum)
S4 (Andarine)
SR9009 (Stenabolic)
SR9011
YK11
GW501516(GSK-516)
AICAR
S-23
LGD-3303
GW-0742
MK-1775
ACP-105

 

 

 

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Steroid Liquid

 

Single Blend	Muti-Blend
Winstrol 50 (water based,Inj/Oral)	Ripex 225
Winstrol 50 (Oil based,Injection)	Rip Cut 175
Dianabol (dbol) 50 (Oral)	Cut Depot 400
Dianabol (dbol) 50 (Injection)	TMT 300 / 375
Dianabol (dbol) 80 (Injection)	Cutting Blend (Rip Cut 175)
Anadrol 50	TMT Blend 250 / 500
Anavar 50 (Oral)	Tri Blend 180 / 300
DECA 100/200/250/300	Tri Deca 300
NPP 100/200	Tren Test 225
Sustanon 250	Equitest 450
Equipoise 250 / 300	Test Blend 300 / 500
Cypoject 250	Supertest 450
Enanject 250 / 300	Anomass 400
Propionat 100	Test 400
Trenabolic 80 / 100	Mass Stack 500
Trenaject 100 / 150 / 200	Test Blend 450
Masteron Acetate 100	Tri-Tren180
Masteron Enanthate 100	Tri Test 300 / 400
Masteron 150	Nandro Test 450
Primobolan 50	Anodro Test 450
Primoject 100	Pentadex 300
Trestolone acetate(MENT) 50	Testoviron
Clomid 50mg/ml oral	Tungsten 600
Nolvadex 20mg/ml oral	Kevlar(1-Rip)200
Letrozole 5mg/ml(oral)
Anastrozole 5 mg/ml (oral)
	-----------TBC

 

 

Pharma Raw Material SARM Powder Aicar Fat Burning Hormone Powder CAS 2627-69-2 Images