82640-04-8 Anti Estrogen oral Steroids powder of Raloxifene hcl on supply for

Anti Estrogen Steroids raw white powder Raloxifene on supply for anti cancer no 82640-04-8

Product Name: Raloxifene Hcl
Synonyms: Raloxifene Hydrochloride
: 82640-04-8
MF: C28H28ClNO4S
MW: 510.04
MP: 250-253°C
Storage temp: -20°C Freezer
Solubility DMSO: 28 mg/mL, soluble
Appearance: Light-Yellow Solid

2. Raloxifene Hcl Description:

Raloxifene Hcl is an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale yellow solid that is very slightly soluble in water.

EVISTA (raloxifene) is supplied in a tablet dosage form for oral administration. Each EVISTA tablet contains 60 g of raloxifene HCl, which is the molar equivalent of 55.71 mg of free base. Inactive ingredients include anhydrouslactose, carnauba wax, crospovidone, FD&C Blue No. 2 aluminum lake, hypromellose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, propylene glycol,and titanium dioxide.

Raloxifene Hcl is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowingbone loss helps to reduce the risk of fractures.Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body.

Raloxifene Hcl helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.This medication is not recommended for use in women before menopause. It should not be used in children...Side effect: Raloxifene may infrequently cause serious blood clots to form in the legs, lungs, oreyes. Other reactions experienced include leg swelling/pain, trouble breathing, chest pain, vision changes. Raloxifene is a teratogenic drug, i.e., can cause developmental abnormalities such as birth defects.

3. Raloxifene Hcl Application:

May prevent or treat corticosteroid-induced bone loss. American College of Rheumatology states that raloxifene can be offered to selected postmenopausal corticosteroid-treated women who refuse hormone replacement therapy or other antiresorptive agents or in whom such therapies are contraindicated.

Reduction in the incidence of invasive breast cancer inpostmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial).

Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established. Not indicated for the treatment of breast cancer or to reduce the risk of recurrence of breast cancer. 1 Not indicated for reduction in the risk of noninvasive breast cancer.

The role of raloxifene in the prevention and treatment of breast cancer is currently under investigation. There is also a similar mechanism of action of drugs, tamoxifen (tamoxifen), for the treatment of breast cancer has been a long time. It is hoped that Raloxifene will be as effective as tamoxifen with less adverse effects.


Raloxifene (marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

4. Raloxifene Hcl COA:

5. Related Products:

Company Introduction:

(1) High Quality: HZ is a steroids manufacturer with its own lab and factory.
The purity of our product is tested by our quality department before it is shipped to our clients. Mostly steroids are 99% purity and approved by SGS,CTI and ITS.

(2) Favorable Price: Our price meets international market performance and we give the best doiscounted price for our new customers and promotioned price for our regular customers.

(3) Safe Fast Delivery: After receiving your payment,we will have professional package team to arrange your parcel within 12 hours.We can guarantee every goods can be successfully deliveried

(4) Available Shipment Way: EMS,HongKong Post,DHL,TNT,UPS,FedEx,Registered Mail,Air Express,Sea Vessel etc

(5) After-Sale Service: We can offer you good service after you place an order.At the same time,we can offer you some homebrew recipe to make injection.More service is more available to you.

Quality control:

All compounds are NMR tested at Bruker spectrometer. Spectrum data is available upon request.

Service and Certificate:

Over decades, we have been helping multi-national pharmaceutical companies and other customers to source or develop qualified suppliers in China.
For new suppliers, we evaluate sources and audit the manufacturing sites, and then give customers reports and recommendations. For quality control, we test samples according to customers method of analysis (if available) or according to our understanding, and arrange pre-shipment samples if necessary. If development is needed, our extensive quality control experience and experienced R&D partners enable us to offer effective technical and analytical support.
We also provide regulatory documentation help for manufacturers. Intellectual Property protection rules are always strictly followed in our practice. We pay special attention to guarantee clear communication and prompt problem-solving between customers and manufacturers.

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