Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
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Home>Products>Raw Steroid Powder>39791-20-3 Nilestriol Raw Steroid Powder Pharmaceutical Of Female Health

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  • 39791-20-3 Nilestriol Raw Steroid Powder Pharmaceutical Of Female Health
  • 39791-20-3 Nilestriol Raw Steroid Powder Pharmaceutical Of Female Health

39791-20-3 Nilestriol Raw Steroid Powder Pharmaceutical Of Female Health

  • Hongkong Saichuang
  • Raw steroid powder

  • China
  • ISO9001
  • 100grams
  • Negotiated
  • 25kg per drum
  • Within 3-7days after received payment
  • T/T, Western Union, MoneyGram
  • 5000kg per month
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Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd

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  • Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd2020-07-10 09:46:19
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Product Details

Product Name: Nilestriol IUPAC name: (1S,10R,11S,13R,14R,15S)-5-(cyclopentyloxy)-14-ethynyl-15-methyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-2,4,6-triene-13,14-diol Number: 39791-20-3
PubChem: 38346 ChemSpider: 35146 UNII: 7JA3B3IALU
KEGG: D05212 ChEMBL: CHEMBL2104468 Formula: C25H32O3
Molar mass: 380.51978 g/mol

Product Description

 

39791-20-3 Nilestriol Raw Steroid Powder Pharmaceutical Of Female Health

 

Detail :

PRODUCT NAME: Nilestriol

NO: 39791-20-3

USES: ANTI HYPERTENSIVE

MOLECULAR WEIGHT: 380.52

MOLECULAR FORMULA: C25H32O3

CHEMICAL NAME: 3-(Cyclopentyloxy)-17alpha-ethinyl-1,3,5(10)-estratrien-16alpha,17beta-diol;Nylestriol;19-Norpregna-1,3,5(10)-trien-20-yne-16,17-diol,3-(cyclopentyloxy)-, (16a,17a)-;17alpha-Ethynylestra-1,3,5(10)-triene-3,16alpha,17beta-triol 3-cyclopentyl ether

Description:


Menopausal year ranged from 1-26 years. The women were divided randomly into three groups.

Group A: the nylestriol were given 2 mg/2 weeks, 136 es,

Group B: 1 mg/2 weeks, 97 es,

Group C: placebo/2 weeks, 50 es.

The results showed:

(1) High-density-lipoprotein cholesterol increased and low-density-lipoprotein cholesterol decreased in both group A and B (P < 0.05), but not in the placebo group (P < 0.05).

(2) Both the group A and B had significant lessening of serum alkaline phosphatase, ratios of calcium to creatinine and hydroxyproline to creatinine (P < 0.05).

(3) The mineral content of distal and proximal forearm bone remained unchanged in both group A and B (P > 0.05), but decreased significantly in placebos (P < 0.01).

(4) The Kupperman index score in both group A and B decreased significantly in 3 month (P < 0.05).

(5) Curettage were performed 205 times in group A and B. Histological diagnosis revealed neither carcinoma nor atypical endometrial hyperplasia.

(6) No breast cancer was found. In conclusion, nylestriol is a convenient and acceptable drug which was beneficial for relieving climacteric syndrome, preventing osteoporosis and improving lipoprotein lipid pattern.

 

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Name: Nilestriol
Product Name: Nilestriol
No: 39791-20-3
M.F: C25H32O3
M.W: 380.52
Packing: foil bag
Assay: 99
Appearance: White crystalline powder
Place of Origin: China
Brand Name: BETTLI
Certification: GMP,SGS,ISO,KOSHER
Minimum Order Quantity: 10grams
Packaging Details; Very discreet or as required
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin

 

 

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