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Home>Products>Pharmaceutical Raw Materials>No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use
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No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use
- Hongkong Saichuang
Pharmaceutical raw material
- China
- ISO9001
- 100grams
- Negotiated
- foil bag
- Within 3-7days after received payment
- T/T, Western Union, MoneyGram
- 5000kg per month
Hongkong Pengfei Pharmaceutical Technology Co.,LtdChina
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Hongkong Pengfei Pharmaceutical Technology Co.,Ltd2020-07-10 09:46:19
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Product Details
| Product Name: | Altretamine | Trade names: | Hexalen | License data: | US FDA |
| Pregnancy category: | AU | Routes of administration: | Oral (capsules) | ATC code: | L01XX03 |
| Legal status: | AU | Protein binding: | 94% | Synonyms: | 2,4,6-Tris(dimethylamino)-1,3,5-triazine |
| Number: | 645-05-6 | PubChem: | 2123 | IUPHAR/BPS: | 7112 |
| DrugBank: | DB00488 | ChemSpider: | 2038 | UNII: | Q8BIH59O7H |
| KEGG: | D02841 | ChEBI: | CHEBI | ChEMBL: | CHEMBL1455 |
| Formula: | C9H18N6 | Molar mass: | 210.28 g/mol | Appearance: | White crystal powder |
| Assay: | 99% |
Product Description
Pharmaceutical raw material Altretamine white crystal powder for cancer treatment use no 645-05-6
Quck details
| Product name | Altretamine |
| Synonym | 1,3,5-Triazine-2,4,6-triamine,1,3,5-tris(dimethylamino)-s-triazine;2,4,6-Tris(Dimethylamino)-s-triazine;5-triazine-2,4,6-triamine,n,n,n’,n’,n’’,n’’-hexamethyl-3;Aitretamine;ENT 50852;ENT050852645-05-6 |
| 645-05-6 | |
| MF | C9H18N6 |
| MW | 210.28 |
| Assay | 99% |
| Package | 25kg/drum |
| Standard | enterprise Standard |
| Usage | An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic. |
| MOQ | 1kg |
Mechanism
The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Administered orally, altretamine is extensively metabolized on first pass, producing primarily mono- and didemethylated metabolites. Additional demethylation reactions occur in tumor cells, releasing formaldehyde in situ before the drug is excreted in the urine.
The carbinolamine (methylol) intermediates of CYP450-mediated metabolism also can generate electrophilic iminium species that are capable of reacting covalently with DNA guanine andcytosine residues as well as protein. Iminium-mediated DNA cross-linking and DNA-protein interstrand cross-linking, mediated through both the iminium intermediate and formaldehyde, have been demonstrated, although the significance of DNA cross-linking on altretamine antitumor activity is uncertain.
Sample is available
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Specifications
1. Licensed manufacturer
2. 12 years production experience
3. Perfect quality
4. Competitive price
Research & Development
We have a highly qualified and experienced R&D team for research, development, pilot test, commercialized scale production and product registration.
Our Advantages
1. packaging & delivery
We do have professional team for package and shipment.Special & safe way to ship all the products to the destination country no matter the quantity or location.Fast and discreet shipment can be arranged for customs clearance guaranteed, security is the key& we do have reshipping policy.
2. our advantages
We are back to introduce us to more clients again! Actually, we are in the business as a professional raw material lab supplier for over 15 years, we have more than enough experience to handle everything in the right way.
a. Our products did & do be shipped safely to many countries with mass quantity always.
b. We do get professional team, esp., for package & shipment, do have strong connection in shipping system, all the parcels are sent via traceable couriersas UPS, FedEx, DHL & so on, do offer customs clearance guaranteed to the destination country.
c. Products are in prompt stock, chargeable samples are available at any time,can be shipped out immediately upon the requirement.
d. You get the absolutely right choice if want the best stuff & service, high quality,good price, fast and safety delivery guaranteed, we do have reshipping policy once anyuncontrollable incident happen
Contact info:
Smith Sun
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