Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
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Home>Products>Pharmaceutical Raw Materials>No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use

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  • No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use
  • No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use

No 645-05-6 Pharmaceutical Raw Materials Altretamine For Cancer Treatment Use

  • Hongkong Saichuang
  • Pharmaceutical raw material

  • China
  • ISO9001
  • 100grams
  • Negotiated
  • foil bag
  • Within 3-7days after received payment
  • T/T, Western Union, MoneyGram
  • 5000kg per month
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Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd

Hongkong Pengfei Pharmaceutical  Technology  Co.,LtdChina

  • Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd2020-07-10 09:46:19
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Product Details

Product Name: Altretamine Trade names: Hexalen License data: US FDA
Pregnancy category: AU Routes of administration: Oral (capsules) ATC code: L01XX03
Legal status: AU Protein binding: 94% Synonyms: 2,4,6-Tris(dimethylamino)-1,3,5-triazine
Number: 645-05-6 PubChem: 2123 IUPHAR/BPS: 7112
DrugBank: DB00488 ChemSpider: 2038 UNII: Q8BIH59O7H
KEGG: D02841 ChEBI: CHEBI ChEMBL: CHEMBL1455
Formula: C9H18N6 Molar mass: 210.28 g/mol Appearance: White crystal powder
Assay: 99%

Product Description

Pharmaceutical raw material Altretamine white crystal powder for cancer treatment use no 645-05-6

Quck details

Product name Altretamine
Synonym 1,3,5-Triazine-2,4,6-triamine,1,3,5-tris(dimethylamino)-s-triazine;2,4,6-Tris(Dimethylamino)-s-triazine;5-triazine-2,4,6-triamine,n,n,n’,n’,n’’,n’’-hexamethyl-3;Aitretamine;ENT 50852;ENT050852645-05-6
645-05-6
MF C9H18N6
MW 210.28
Assay 99%
Package 25kg/drum
Standard enterprise Standard
Usage An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.
MOQ 1kg


Mechanism

The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Administered orally, altretamine is extensively metabolized on first pass, producing primarily mono- and didemethylated metabolites. Additional demethylation reactions occur in tumor cells, releasing formaldehyde in situ before the drug is excreted in the urine.

The carbinolamine (methylol) intermediates of CYP450-mediated metabolism also can generate electrophilic iminium species that are capable of reacting covalently with DNA guanine andcytosine residues as well as protein. Iminium-mediated DNA cross-linking and DNA-protein interstrand cross-linking, mediated through both the iminium intermediate and formaldehyde, have been demonstrated, although the significance of DNA cross-linking on altretamine antitumor activity is uncertain.

Sample is available

1 day for ready goods , fast shippment ,door to door within 5-7 business days Professional after sale service

Specifications


1. Licensed manufacturer
2. 12 years production experience
3. Perfect quality
4. Competitive price

Research & Development


We have a highly qualified and experienced R&D team for research, development, pilot test, commercialized scale production and product registration.

Our Advantages

1. packaging & delivery

We do have professional team for package and shipment.Special & safe way to ship all the products to the destination country no matter the quantity or location.Fast and discreet shipment can be arranged for customs clearance guaranteed, security is the key& we do have reshipping policy.

2. our advantages

We are back to introduce us to more clients again! Actually, we are in the business as a professional raw material lab supplier for over 15 years, we have more than enough experience to handle everything in the right way.

a. Our products did & do be shipped safely to many countries with mass quantity always.

b. We do get professional team, esp., for package & shipment, do have strong connection in shipping system, all the parcels are sent via traceable couriersas UPS, FedEx, DHL & so on, do offer customs clearance guaranteed to the destination country.

c. Products are in prompt stock, chargeable samples are available at any time,can be shipped out immediately upon the requirement.

d. You get the absolutely right choice if want the best stuff & service, high quality,good price, fast and safety delivery guaranteed, we do have reshipping policy once anyuncontrollable incident happen

Contact info:

Smith Sun


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