Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
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Home>Products>Pharmaceutical Raw Materials>Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti

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  • Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti
  • Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti
  • Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti
  • Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti

Weight Loss Steroids Stuff Of Orlistat Raw White Powder Material For Pharmaceuti

  • Hongkong Saichuang
  • Pharmaceutical raw material

  • China
  • ISO9001
  • 100grams
  • Negotiated
  • 1kg for Foil bag
  • Within 3-7days after received payment
  • T/T, Western Union, MoneyGram
  • 5000kg per month
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Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd

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  • Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd2020-07-10 09:46:19
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Product Details

Product Name: Orlistat Trade names: Xenical, Alli MedlinePlus: a601244
License data: EU EMA Pregnancy category: AU Routes of administration: Oral
ATC code: A08AB01 Legal status: AU Bioavailability: Negligible
Protein binding: >99% Metabolism: In the GI tract IUPAC name: (S)-((S)-1-((2S,3S)-3-Hexyl-4-oxooxetan-2-yl)tridecan-2-yl) 2-formamido-4-methylpentanoate
Synonyms: tetrahydrolipstatin Number: 96829-58-2 PubChem: 3034010
IUPHAR/BPS: 5277 DrugBank: DB01083 ChemSpider: 2298564
UNII: 95M8R751W8 KEGG: D04028 ChEBI: CHEBI
ChEMBL: CHEMBL175247 Formula: C29H53NO5 Molar mass: 495.735 g/mol
Appearance: White crystal powder Assay: 98%

Product Description

Loss weight drug stuff of Orlistat raw white powder material for pharmaceutical use no 96829-58-2

Product name: Orlistat
: 96829-58-2
Molecular Formula: C29H53NO5
Molecualr Weight: 495.73
Assay: 99%
Grade:Pharmaceutical Grade
Appearance:White Crystalline Powder

Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity


Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet. Orlistat is for use only in adults.


The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat.

Fat Loss Mechanism

Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool.

This medication is used along with a doctor-approved reduced-calorie diet, exercise, and behavior modification program to help significantly overweight (obese) persons lose weight. Taking orlistat can also help prevent you from regaining the weight you have lost. Losing weight and keeping it off can reduce the many health risks that obesity causes, including heart disease, diabetes, high blood pressure, some forms of cancer, certain breathing problems, and a shorter life span.

Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

Fat Loss Effect

Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat.After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.

The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).

Orlistat Dosage

Orlistat is usually taken 3 times a day during every meal containing fat. The average dosage is a 120mg per day. Due to the fact that Xenical may decrease the absorption of vitamins and it is useful to take a multivitamin once a day at bedtime. While taking this drug bodybuilders and athletes should follow their diet, medication, and exercise routines very closely.

Specification

Items Specification Items
Appearance white or almost white crystalline powder,smell less
Melting Point 42.0~46.0°C
Specific Rotation -31°~-39°(CHCl3,C=1)
Identification The result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one.
Related Substances ≤ 0.5%
Total impurity ≤ 1.0%
Single impurity ≤ 0.1%
≤ 290ppm
≤ 5000ppm
Residual on Ignition ≤0.1%
Sulphate ≤ 0.05%
Heavy Metal ≤ 20ppm
Purity ≤ 99.0% ~ 99.9%

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