Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd
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Home>Products>Pharmaceutical Raw Materials>Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4

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  • Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4
  • Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4
  • Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4
  • Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4

Tretinoin Raw Material Yellow Powder For Skin Pharmaceutical Use No 302-79-4

  • Hongkong Saichuang
  • Skin pharmaceutical raw material

  • China
  • ISO9001
  • 10grams
  • Negotiated
  • 1,2,5 kg / tin
  • Within 3-7days after received payment
  • T/T, Western Union, MoneyGram
  • 5000kg per month
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  • Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd2020-07-10 09:46:19
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Product Details

Product Name: Tretinoin Trade names: Vesanoid, Avita, Renova, Retin-a License data: US DailyMed
Pregnancy category: AU Routes of administration: topical, by mouth ATC code: D10AD01,L01XX14
Legal status: AU Protein binding: > 95% Biological half-life: 0.5-2 hours
IUPAC name: (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid Number: 302-79-4 PubChem: 444795
DrugBank: DB00755 ChemSpider: 392618 UNII: 5688UTC01R
KEGG: D00094 ChEBI: CHEBI ChEMBL: CHEMBL38
Formula: C20H28O2 Molar mass: 300.4412 g/mol Purity: 99%
Appearance: Yellow crystal powder

Product Description

Tretinoin raw material yellow powder for skin pharmaceutical manufacture no 302-79-4

Product name Tretinoin
Synonyms TRETINOIN;TRETINOIN VITAMIN A ACID;TRANS-RETINOIC ACID;TRANS VITAMIN A ACID;VITAMIN A ACID;VITAMIN A ACID, ALL-TRANS;RETINOIC ACID;RETINOIC ACID, ALL TRANS
Original China
302-79-4
MF C20H28O2
Brand name Fulu
Delivery time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance Yellow-Orange Powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin,Banktransfer ect.
Minimum Order Quantity Negotiable
Price Negotiable
Usage Blackhead-Acne-Lesions Treating

Description:


1. Tretinoin is commonly used in dermatology drugs, which is the department of vitamin A

(Victoria methanol) metabolic intermediates.It mainly affects the growth of bones and epithelial

metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation

and differentiation of keratinocytes, so hyperkeratosis can be back to normal.

2. Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain

therapeutic effect, treat a variety of skin diseases. The use of the drug can penetrate topical skin

quickly, enable significantly increased epithelial cell turnover. This class of drugs has strong and

rapid inhibition on the secretion of the sebaceous glands, can reduce sebum secretion. In

addition, the product also has anti-tumor, promote wound healing and anti-inflammatory effects.

3. It is a yellow needle crystal, with a similar smell of vitamin acetate. Soluble in methanol, ethanol,

acetone, also in vegetable oil and fatty. In e of light, it is thermal instability, suck up moisture in

the air, polymerization and metamorphism in water. The melting point of all trans-vitamin A acid is

182 ~ 180°C, the melting range of which is mixed with a small amount of isomers is 170 ~ 190°C.

4. This product can induce epidermal hyperplasia, and improve the granular layer and the cell

layer thickness.It can influence the silk protein process and the formation of cross-linked film and

promote the differentiation of epidermal granular layer cells in the late stage of the differentiation

of the epidermal cells by affecting K10, K1 keratin solution.

Usage:

Used in abnormal acne, ichthyosis and abnormal type of psoriasis. For the treatment of acne

vulgaris, psoriasis, ichthyosis, lichen planus, Mao Fahong rosea, follicular keratosis, squamous

cell carcinoma and melanoma, disease.

Pharmacology: Epidermal keratinocytes, dermal melanin cells and fibroblasts are the target cells

of A retinoic acid important. A retinoic acid can affect the formation of melanin melanin cells, its

role is more than point, has inhibitory effect on tyrosine hydroxylase, Doba oxidase and two

hydroxyindole oxidase three catalytic activity, thereby reducing the formation of melanin, reduce

skin pigmentation.

Function:

1. Used for usual acne, lichen planus, white spot, hair red pityriasis and facial pityriasis simplex

2. Also can be used as an auxiliary therapy for psoriasis.

3. Can also be used in the treatment of multiple verruca vulgaris, and abnormal keratinization of

various skin diseases such as ichthyosis, hair follicle keratinization disorder

4. For cancer prevention and treatment of precancerous lesions, Such as white spot of the oral

mucosa, laryngeal papilloma, stunting disease

5. Used for skin malignant tumor such as squamous cell carcinomas and basal cell carcinoma,

mycosis enzyme disease

6. For acute early young granulocyte leukemia.

Tretinoin COA

Item Standard Result
Appearance Yellow or light yellow crystalline powder Conforms
Melting Point About 182ºC 181.5~182.5ºC
Solubility Conforms Conforms
Identification Positive Positive
Loss on drying ≤0.5% 0.22%
Heavy metais ≤0.002 Conforms
Residue on ignition ≤0.1% 0.06%
Related substsnces ≤0.5% 0.20%
Isotretinoin ≤0.5% 0.42%
Assay 97.0~102.0% 99.70%

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