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Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No
- Hongkong Saichuang
Pharmaceutical raw material
- Hubei China
- ISO9001
- 100grams
- Negotiated
- Within 3-7days after received payment
- T/T, Western Union, MoneyGram
- 5000kg per month
Hongkong Pengfei Pharmaceutical Technology Co.,LtdChina
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Hongkong Pengfei Pharmaceutical Technology Co.,Ltd2020-07-10 09:46:19
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Product Details
| Product Name: | Clobetasol propionate | Routes of administration: | Topical only | ATC code: | D07AD01 |
| Legal status: | In general | Number: | 25122-46-7 | PubChem: | 32798 |
| DrugBank: | DB01013 | ChemSpider: | 30399 | UNII: | 779619577M |
| ChEBI: | CHEBI | ChEMBL: | CHEMBL1159650 | Formula: | C25H32ClFO5 |
| Molar mass: | 466.97 g/mol | Appearance: | White crystal powder | Assay: | 99.5% |
Product Description
Good quality Clobetasol propionate raw material white crystal powder For Anti - inflammatory no 25122-46-7
Clobetasol propionate(Dermovate) COA
Product |
Clobetasol Propionate |
||
Batch Size |
10.2kg |
Mfg.Date |
Nov 7, 2016 |
Report Date |
Nov 7, 2016 |
Exp Date |
Nov, 2019 |
Reference |
USP35 |
||
Item |
Specification |
Result |
Appearance |
White to cream, crystalline powder |
White crystalline powder |
Identification (by IR) |
Conforms to the CRS spectrum |
Conforms |
Melting Point |
Approximately 196 °C |
196°C |
Specific rotation |
+98°~+104°(dried substance) |
+99.7° |
Loss on drying |
≤2.0% |
0.2% |
Residue on ignition |
≤0.1% |
0.06% |
Heavy metals |
≤20ppm |
Conforms |
Related substance (by HPLC) |
Any impurity ≤1.0% |
0.22% |
Total impurities ≤2.0% |
0.31% |
|
Assay(by HPLC) |
Contains 97.0% to 102% of C25H32CIFO5 calculated on dried basis |
99.9% |
Residual solvents |
Ethanol ≤3000ppm |
262ppm |
Aceton ≤500ppm |
Undetected(LOD 4ppm) |
|
Pyriding ≤100ppm |
Undetected(LOD 3ppm) |
|
N,N-Dimethylformamide ≤100ppm |
Undetected(LOD 10ppm) |
|
Conclusion |
Meet the specification according to USP35 |
|
Clobetasol propionate(Dermovate) Description and Application:
Clobetasol propionate is a synthetic high topical cortico steroids.
Dermovate has a strong anti-inflammatory, anti itching and capillary contraction, the anti-inflammatory effects of hydrocortisone is about 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. At the same time has an inhibitory role in cell mitosis, can effectively penetrate into the skin stratum corneum. External apply to chronic eczema, psoriasis, neurodermatitis, palmoplantar pustulosis, lichen planus, discoid lupus erythematosus, glucocorticoid, topical treatment of pruritic effective and non inflammatory skin disease. Has the inhibitory effect of anti-inflammatory, anti allergic, anti proliferation, immune.
Clobetasol propionate(Dermovate) Basic Info:
: 25122-46-7
Assay:99.5%
Molecular Formula:C25H32ClFO5
Molecular Weight:466.97
EINECS: 246-634-3
Density: 1.28 g/cm3
Melting Point: 195.5-197 °C
Boiling Point: 569 °C at 760 mmHg
Flash Point: 297.9 °C
Appearance: White crystalline powder. In choro form soluble in acetic acid, dissolved in the methanol and ethanol is soluble in water insoluble.
Usage: Adrenal cortical hormone and adrenocorticotropic hormone class medicine.
Our Advantage:
1 High quality with competitive price:
2 Fast and safe delivery:
3 Customers throughout the world:
4 15 years in the field
|
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