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Home>Products>Pharmaceutical Raw Materials>Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No

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  • Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No
  • Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No
  • Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No
  • Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No

Clobetasol Propionate Pharmaceutical Raw Materials For Anti - Inflammatory No

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  • Hongkong Pengfei Pharmaceutical  Technology  Co.,Ltd2020-07-10 09:46:19
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Product Details

Product Name: Clobetasol propionate Routes of administration: Topical only ATC code: D07AD01
Legal status: In general Number: 25122-46-7 PubChem: 32798
DrugBank: DB01013 ChemSpider: 30399 UNII: 779619577M
ChEBI: CHEBI ChEMBL: CHEMBL1159650 Formula: C25H32ClFO5
Molar mass: 466.97 g/mol Appearance: White crystal powder Assay: 99.5%

Product Description

Good quality Clobetasol propionate raw material white crystal powder For Anti - inflammatory no 25122-46-7

Clobetasol propionate(Dermovate) COA


Product

Clobetasol Propionate

Batch Size

10.2kg

Mfg.Date

Nov 7, 2016

Report Date

Nov 7, 2016

Exp Date

Nov, 2019

Reference

USP35

Item

Specification

Result

Appearance

White to cream, crystalline powder

White crystalline powder

Identification (by IR)

Conforms to the CRS spectrum

Conforms

Melting Point

Approximately 196 °C

196°C

Specific rotation

+98°~+104°(dried substance)

+99.7°

Loss on drying

≤2.0%

0.2%

Residue on ignition

≤0.1%

0.06%

Heavy metals

≤20ppm

Conforms

Related substance (by HPLC)

Any impurity ≤1.0%

0.22%

Total impurities ≤2.0%

0.31%

Assay(by HPLC)

Contains 97.0% to 102% of C25H32CIFO5 calculated on dried basis

99.9%

Residual solvents

Ethanol ≤3000ppm

262ppm

Aceton ≤500ppm

Undetected(LOD 4ppm)

Pyriding ≤100ppm

Undetected(LOD 3ppm)

N,N-Dimethylformamide ≤100ppm

Undetected(LOD 10ppm)

Conclusion

Meet the specification according to USP35

Clobetasol propionate(Dermovate) Description and Application:

Clobetasol propionate is a synthetic high topical cortico steroids.

Dermovate has a strong anti-inflammatory, anti itching and capillary contraction, the anti-inflammatory effects of hydrocortisone is about 112.5 times, 2.3 times of betamethasone sodium phosphate, 18.7 times fluocinolone. At the same time has an inhibitory role in cell mitosis, can effectively penetrate into the skin stratum corneum. External apply to chronic eczema, psoriasis, neurodermatitis, palmoplantar pustulosis, lichen planus, discoid lupus erythematosus, glucocorticoid, topical treatment of pruritic effective and non inflammatory skin disease. Has the inhibitory effect of anti-inflammatory, anti allergic, anti proliferation, immune.

Clobetasol propionate(Dermovate) Basic Info:

: 25122-46-7
Assay:99.5%
Molecular Formula:C25H32ClFO5
Molecular Weight:466.97
EINECS: 246-634-3
Density: 1.28 g/cm3
Melting Point: 195.5-197 °C
Boiling Point: 569 °C at 760 mmHg
Flash Point: 297.9 °C

Appearance: White crystalline powder. In choro form soluble in acetic acid, dissolved in the methanol and ethanol is soluble in water insoluble.
Usage: Adrenal cortical hormone and adrenocorticotropic hormone class medicine.

Your Attention:
1/ Packing: Discreet package/foil bag
2/ Deliver: DHL, EMS, UPS, TNT, FedEX
3/ Lead time: in 24 hours after payment
4/ Time on the way: About 3~7 working days(door to door)
5/ Customs clearance rate: Above 99%
6/ After sale service: we guarantee products receive safety, If not, same one reship unconditional.

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