HGH Human Growth Peptides , Lyophilized Powder Hexarelin 140703-51-1

Hexarelin Functions and Traits

Hexarelin is comprised of a chain of amino acids that when administered stimulates the pituitary in a pulsating fashion causing it to release more GH into the body. Unfortunately, at this time it is not fully understood how Hexarelin causes such a strong increase in GH compared to say GHRP-6; data merely shows that the increase is significantly more.

The use of Hexarelin has also been shown to increase prolactin and cortisol levels in the body, far more so than other GH products. Prolactin increases should not be as strong as they may be with certain anabolic steroid, but they may be significant in some cases. Hexarelin will not increase Ghrelin levels in the body like GHRP-6 despite being very similar on a structural basis.

Data has also shown Hexarelin to be one of the faster acting GH products on the market but also one of the few that stops working after a set amount of time. GH levels should increase quickly and in a beneficial manner in as little as four weeks. However, use past the sixteen week mark has been shown to produce little to no results. Use of any worth will normally fall in the 8-12 week range with 4-6 weeks of no use (minimum) between Hexarelin cycles. The peptide will not render pituitary function (GH production) post use as will anabolic steroid in regards to the testicles, but it does appear to have a short lived actionable period of use.

Description:
secretagogue receptor is a G protein-coupled receptor that binds ghrelin and plays a role in energy homeostasis and regulation of body weight.

Hexarelin is a six-amino acid peptide. Studies have shown that hexarelin is actually more effective and longer lasting than releasing hormone (GHRH). It is also known that GHRP-6 has a synergistic effect with GHRH, causing a far greater release than either of these substances alone. By combining GHRP-6 with Hexarelin, a more potent GH releasing peptide combination is created than ever heard of.

The potential clinical usefulness of these GH releasing hexapeptides is also reinforced by observations that long-term administration produces elevations in circulating concentrations. Long term treatment with GHRP-6 similarly has been shown to elevate serum as well asbinding protein-3 concentrations and promote linear growth.

Application:
Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cades in different cellular systems.

One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.

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